Class 11 Biology Chapter 18 Neural Control and Coordination — Formulas & Key Points
Neural Control and Coordination is Chapter 18 in NCERT Class 11 Biology and forms the foundation for understanding how the human nervous system integrates stimuli and coordinates responses. Unlike purely descriptive chapters, this unit involves specific voltage values, transmission speeds, neurotransmitter names, and reflex pathways that students must recall accurately. This formula sheet presents every key definition, structural component, and mechanism in tabulated format, supported by mnemonics and worked examples to ensure rapid, error-free revision for CBSE board and competitive exams.
Key takeaways
- ✓Neuron structure includes dendrites (receive signals), cell body (soma), axon (transmits signals), and synaptic terminals; myelinated axons conduct impulses faster via saltatory conduction.
- ✓Action potential propagation follows All-or-None law: either full depolarisation (from −70 mV to +30 mV) or no impulse; threshold typically −55 mV in human neurons.
- ✓Synapse transmission involves neurotransmitter release (acetylcholine, norepinephrine) across synaptic cleft (~20–30 nm), ensuring unidirectional signal flow.
- ✓Reflex arc comprises receptor → sensory neuron → integration centre (spinal cord/brain) → motor neuron → effector; knee-jerk reflex involves only two neurons (monosynaptic).
- ✓Resting potential (−70 mV) maintained by Na⁺-K⁺ pump (3 Na⁺ out, 2 K⁺ in per ATP); depolarisation occurs when Na⁺ channels open, repolarisation when K⁺ channels open.
- ✓Human brain divisions: forebrain (cerebrum, thalamus, hypothalamus), midbrain (corpora quadrigemina), hindbrain (pons, cerebellum, medulla); cerebrum has 2–4 mm thick cortex.
- ✓Common errors include confusing afferent (sensory) with efferent (motor) neurons, mixing up sympathetic vs parasympathetic effects, and incorrect resting potential polarity notation.
Core Definitions and Terminology — Neural Control Fundamentals
- Neuron: structural and functional unit of the nervous system; capable of generating and transmitting nerve impulses.
- Axon: single long fibre that conducts impulses away from the cell body; may be myelinated (faster conduction) or non-myelinated.
- Dendrites: short, branched fibres that receive stimuli and conduct impulses toward the cell body.
- Synapse: junction between two neurons where transmission occurs chemically via neurotransmitters; ensures unidirectional flow.
- Reflex action: involuntary, rapid, automatic response to a stimulus; does not require conscious thought (e.g., withdrawal of hand from hot object).
- Resting potential: electrical potential difference across neuronal membrane at rest, approximately −70 mV (inside negative relative to outside).
- Action potential: rapid reversal of membrane potential (depolarisation to +30 mV, then repolarisation) when neuron is stimulated beyond threshold.
- Saltatory conduction: impulse 'jumps' from one Node of Ranvier to the next in myelinated fibres, achieving speeds up to 120 m/s.
Neuron Structure — Key Components and Functions Table
Membrane Potentials and Ion Movements — Formulae and Values
- Resting potential: Vₘ ≈ −70 mV (inside negative); [K⁺] inside ~140 mM, outside ~5 mM; [Na⁺] inside ~15 mM, outside ~145 mM.
- Threshold potential: Vₘ(threshold) ≈ −55 mV; stimuli exceeding this trigger all-or-none action potential.
- Peak depolarisation: Vₘ(peak) ≈ +30 mV during action potential upstroke (Na⁺ influx phase).
- Repolarisation: K⁺ efflux returns Vₘ back toward resting; hyperpolarisation may reach −80 mV transiently.
- Na⁺-K⁺ pump stoichiometry: 3 Na⁺ out, 2 K⁺ in per 1 ATP hydrolysed; maintains gradients and contributes ~−5 mV to resting potential.
- Conduction velocity: myelinated A-alpha fibres ~70–120 m/s; unmyelinated C fibres ~0.5–2 m/s; velocity ∝ diameter and myelination.
Synapse Mechanism — Neurotransmitter Release and Reception
- Synaptic cleft width: ~20–30 nm; neurotransmitter diffusion time ~0.5 ms (synaptic delay).
- Common neurotransmitters: acetylcholine (ACh) at neuromuscular junctions; norepinephrine, dopamine, serotonin, GABA in CNS.
- Excitatory synapse: neurotransmitter opens Na⁺ channels → depolarisation (EPSP); if sum of EPSPs reaches threshold, postsynaptic neuron fires.
- Inhibitory synapse: neurotransmitter opens Cl⁻ or K⁺ channels → hyperpolarisation (IPSP); reduces likelihood of firing.
- Acetylcholinesterase: enzyme in synaptic cleft that hydrolyses ACh into acetate + choline, terminating signal within ~1 ms.
- Summation: spatial (multiple synapses active simultaneously) or temporal (rapid successive stimuli from one synapse) integration at axon hillock.
Reflex Arc Components — Pathway and Example Reflexes
- Receptor: sensory structure (e.g., muscle spindle, pain receptor, photoreceptor) that detects stimulus and generates nerve impulse.
- Sensory neuron: carries impulse from receptor to CNS dorsal horn (spinal) or brain; cell body in dorsal root ganglion.
- Integration centre: spinal cord or brain region where sensory input is processed; may involve one synapse (monosynaptic) or multiple (polysynaptic).
- Motor neuron: carries impulse from CNS ventral horn to effector; axon exits via ventral root of spinal nerve.
- Effector: muscle (contracts) or gland (secretes) to produce response; completes the reflex arc.
- Monosynaptic reflex: one synapse (sensory-motor) in CNS; example: knee-jerk reflex (~50 ms total time).
- Polysynaptic reflex: two or more synapses (includes interneurons); example: withdrawal reflex, crossed-extensor reflex.
Central Nervous System (CNS) — Brain and Spinal Cord Divisions
- Forebrain: cerebrum (two hemispheres, corpus callosum connecting them), thalamus (relay station), hypothalamus (autonomic and endocrine control).
- Midbrain: corpora quadrigemina (four lobes; superior pair visual reflexes, inferior pair auditory reflexes), cerebral peduncles (motor tracts).
- Hindbrain: pons (relays signals, regulates respiration with medulla), cerebellum (coordinates movements, balance), medulla (controls heart, respiration, vasomotor centre).
- Grey matter: neuron cell bodies and dendrites; forms cortex in cerebrum and cerebellar cortex; inner H-shape in spinal cord.
- White matter: myelinated axons; forms tracts in brain and outer columns in spinal cord (dorsal, lateral, ventral).
- Meninges: dura mater (tough outer), arachnoid (web-like middle), pia mater (delicate inner); cerebrospinal fluid in subarachnoid space cushions CNS.
- Spinal nerves: 31 pairs (8 cervical, 12 thoracic, 5 lumbar, 5 sacral, 1 coccygeal); each has dorsal sensory root and ventral motor root.
Peripheral Nervous System (PNS) — Cranial and Spinal Nerves
- Cranial nerves: 12 pairs; some purely sensory (I, II, VIII), some purely motor (III, IV, VI, XI, XII), some mixed (V, VII, IX, X).
- Spinal nerves: 31 pairs; each formed by dorsal (sensory) root + ventral (motor) root joining outside spinal cord.
- Sympathetic division: thoracolumbar outflow; short preganglionic, long postganglionic fibres; neurotransmitter norepinephrine at most targets.
- Parasympathetic division: craniosacral outflow; long preganglionic, short postganglionic; neurotransmitter acetylcholine at all synapses.
- Dual innervation examples: heart (sympathetic ↑ rate, parasympathetic ↓ rate), pupils (sympathetic dilates, parasympathetic constricts), digestion (sympathetic inhibits, parasympathetic stimulates).
- Mnemonic for cranial nerves: 'On Old Olympus Towering Tops A Finn And German Viewed Some Hops' (Olfactory, Optic, Oculomotor, Trochlear, Trigeminal, Abducens, Facial, Auditory, Glossopharyngeal, Vagus, Spinal accessory, Hypoglossal).
Common Mistakes, Mnemonics and Memory Tricks
- Afferent vs Efferent: Afferent = Arriving (sensory to CNS); Efferent = Exiting (motor from CNS).
- Resting potential sign: inside −70 mV, outside 0 mV (reference); never write +70 mV for resting!
- Sympathetic = 'Sympathy for stress' → ↑ heart rate, ↑ BP, dilate pupils, inhibit digestion.
- Parasympathetic = 'Para = peaceful' → ↓ heart rate, constrict pupils, stimulate digestion.
- Cranial nerves mnemonic: 'On Old Olympus Towering Tops A Finn And German Viewed Some Hops' (I–XII sequence).
- Node of Ranvier = gap; myelin sheath = insulation; action potential jumps node-to-node (saltatory conduction).
- All-or-None law: threshold met → full AP (+30 mV peak); subthreshold → no AP (not a graded response).
- Refractory period: absolute ~1 ms (no stimulus works), relative ~2–4 ms (strong stimulus may work).
Solved Example 1 — Conduction Velocity Comparison
Solved Example 2 — Reflex Arc Time Calculation
Solved Example 3 — Brain Function Mapping
One-Glance Last-Minute Revision Box
- Neuron: dendrite → soma → axon → synapse
- Vₘ(rest) = −70 mV; Vₘ(threshold) = −55 mV; Vₘ(peak) = +30 mV
- Myelinated conduction: 70–120 m/s (saltatory); unmyelinated: 0.5–2 m/s
- Synapse: chemical transmission; unidirectional; ACh common neurotransmitter
- Reflex arc: receptor → sensory → CNS → motor → effector
- Brain: forebrain (cerebrum, thalamus, hypothalamus), midbrain, hindbrain (pons, cerebellum, medulla)
- 12 cranial nerves; 31 spinal nerves; sympathetic (stress), parasympathetic (rest)
- Na⁺-K⁺ pump: 3 Na⁺ out, 2 K⁺ in per ATP; maintains resting potential
Frequently asked questions
What is the resting membrane potential of a typical human neuron and how is it maintained?+
Why is the All-or-None law important in nerve impulse conduction?+
What is saltatory conduction and why is it faster than continuous conduction?+
How does a synapse ensure unidirectional transmission of nerve impulses?+
What is the difference between a monosynaptic and a polysynaptic reflex arc?+
Which part of the brain controls balance and coordination, and what happens if it is damaged?+
What are the main differences between the sympathetic and parasympathetic nervous systems?+
How many pairs of cranial and spinal nerves are present in humans, and what is their function?+
Why do Class 11 students find Neural Control and Coordination challenging compared to other Biology chapters?+
Where can I get 24×7 doubt-solving and personalised practice for Chapter 18 Neural Control and Coordination?+
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